Sharon, a woman with moderate Binge Eating Disorder, smiling.

Sharon, diagnosed with moderate B.E.D. and treated with Vyvanse


When considering Vyvanse (lisdexamfetamine dimesylate) as part of your B.E.D. treatment plan, it's important to understand the potential risks. Talk to your doctor and see below to learn more about some of the potential risks and side effects of Vyvanse.

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Abuse and dependence

Vyvanse is a federally controlled substance (CII) because it can be abused or lead to dependence. Keep Vyvanse in a safe place to prevent misuse and abuse. Selling or giving away Vyvanse may harm others and is against the law.

Tell the doctor if you have ever abused or been dependent on alcohol, prescription medicines, or street drugs.

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Who should not take Vyvanse?

You should not take Vyvanse if you are:

  • Taking or have taken an anti-depression medicine called a monoamine oxidase inhibitor (MAOI) within the past 14 days
  • Sensitive or allergic to, or had a reaction to, other stimulant medicines


Vyvanse is a stimulant medicine. The following have been reported with use of stimulant medicines.

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Heart-related problems, including:

  • Sudden death in people who have heart problems or heart defects
  • Sudden death, stroke, and heart attack in adults
  • Increased blood pressure and heart rate

Tell the doctor about any heart problems, heart defects, and/or high blood pressure, or if you have a family history of these problems. The doctor should check your blood pressure and heart rate regularly during treatment.

Call the doctor right away if you have any signs of heart problems such as chest pain, shortness of breath, or fainting while taking Vyvanse.

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Mental (psychiatric) problems, including:

  • New or worse behavior and thought problems
  • New or worse bipolar illness
  • New psychotic symptoms, such as:
    • Seeing things or hearing voices that are not real
    • Believing things that are not true
    • Being suspicious
  • New manic symptoms

Tell your doctor about any mental problems you have, or if you have a family history of suicide, bipolar illness, or depression.

Call the doctor to discuss any new or worsening mental symptoms or problems while taking Vyvanse.

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Circulation problems in fingers and toes (peripheral vasculopathy, including Raynaud's phenomenon):

  • Fingers or toes may feel numb, cool, painful, sensitive to temperature and/or change color from pale, to blue, to red.

Tell your doctor if you have numbness, pain, skin color change, or sensitivity to temperature in fingers or toes.

Call the doctor to report these signs or symptoms or if any unexplained wounds on fingers or toes appear while taking Vyvanse.

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Symptoms of serotonin syndrome, including:

  • Agitation, hallucinations, coma, or changes in mental status
  • Problems controlling movements or muscle twitching, stiffness, or tightness
  • Fast heartbeat, sweating, or fever
  • Nausea, vomiting, or diarrhea

Call your doctor or go to the emergency room if symptoms occur. Serotonin syndrome may occur if Vyvanse is taken with certain medicines and may be life-threatening.

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Tell your doctor if you are pregnant, breastfeeding, or plan to become pregnant or breastfeed.

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Tell your doctor if you have any kidney problems. Your doctor may lower the dose.

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The most common side effects of Vyvanse reported in studies of adults with moderate to severe B.E.D. were:

  • dry mouth
  • decreased appetite
  • constipation
  • anxiety
  • trouble sleeping
  • increased heart rate
  • feeling jittery

These are not all the possible side effects of Vyvanse. Ask the doctor or pharmacist for more information and talk to the doctor about any side effects you may be experiencing.

Please see the Vyvanse Prescribing Information and Medication Guide for more information. If you are experiencing any side effects while taking Vyvanse, let your doctor know.

Proper use of prescription stimulant medication

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